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tecovirimat will enhance the level or outcome of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Check. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Watch for adverse outcomes if coadministered with sensitive substrates of these enzymes.cyclophosphamide will increase the degree or influence of modafinil by infl